Damask Rose-Mediated ZnO/HAp Nanocomposite: A Novel Approach for Biomedical Application

Yasotha P; Kalaiselvi V; Gopi S; Anusha Devi V; Sarathamani T

doi:10.34256/famr2522

Yasotha P Department of Physics, Navarasam Arts and Science College for Women, Arachalur, Erode, Tamil Nadu, India
Kalaiselvi V Department of Internet of Things, Vellalar College for women, Thindal, Erode, Tamil Nadu, India.
Gopi S Department of Physics, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore, India
Anusha Devi V Department of Physics, Navarasam Arts and Science College for Women, Arachalur, Erode, Tamil Nadu, India
Sarathamani T Department of Physics, Navarasam Arts and Science College for Women, Arachalur, Erode, Tamil Nadu, India

Keywords: Antibacterial activity, ZnO/HAp nanocomposites, Green synthesis, XRD, FTIR, UV-Visible

Abstract

In this study, zinc oxide/hydroxyapatite (ZnO/HAp) nanocomposites were successfully synthesized via a green method using Damask rose extract as a natural reducing and stabilizing agent. The use of this plant extract not only provides an eco-friendly and cost-effective synthesis route but also imparts additional biological functionalities to the nanocomposites due to the presence of bioactive phytochemicals. The synthesized ZnO/HAp nanocomposites were characterized by various analytical techniques. X-ray diffraction (XRD) analysis confirmed the crystalline nature and phase purity of both ZnO and HAp, with well-defined diffraction peaks. Fourier-transform infrared spectroscopy (FTIR) revealed functional groups associated with metal–oxygen bonding as well as organic moieties derived from the plant extract. UV–Visible spectroscopy exhibited strong absorption in the UV region, validating the successful formation of ZnO nanoparticles and highlighting their potential for biomedical optical applications. The antimicrobial performance of the ZnO/HAp nanocomposites was evaluated against different pathogenic strains. Antibacterial activity was significant against both Gram-positive (Streptococcus mutans) and Gram-negative (Fusobacterium nucleatum) bacteria, as indicated by prominent inhibition zones. Furthermore, antifungal assays demonstrated notable inhibitory effects against Cryptococcus neoformans, confirming the broad-spectrum antimicrobial efficacy of the synthesized nanocomposites. The novelty of this work lies in the utilization of Damask rose extract for the green synthesis of ZnO/HAp nanocomposites, which not only reduces the reliance on hazardous chemical methods but also enhances the bioactivity of the material, making it a promising candidate for biomedical applications.

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